General Assembly Meeting Thursday, May 5th 10:00 – 13:00

General Assembly Meeting - 2022

A virtual (Zoom) and face-to-face meeting in Paris, France

followed by Lunch

Other Logistical information to follow nearer the time

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The 2020 GA meeting which normally takes place in May was postponed to November 4th due to the global pandemic. The November 4th meeting which was virtual saw 20 attendees and lasted an hour as most of the GA mandated task/decisions were addressed by way of votes prior to the meeting. Chaired by Interim Chairman Dr Bernd Friede, the meeting though brief was effective with some key decisions taken as follows:

Some highlights:

  • Executive Committee: A new Executive team was endorsed with the 2nd Vice-Chairman becoming the Chairman and Secretary General maintained to ensure continuity
  • Non-EU letter of Access Fees: Letter of Access fees and administration fees for non-EU REACH-Like regulations per substance, per legal entity for non-MARA members was established
  • Members involvement in Non-EU regulations: MARA members wishing to register substances in non-EU REACH-like regulations will only pay administration fees as they own the data generated by MARA
  • Technical update: Three dossiers updated this year lead to a new classification for manganese based UVCB’s
  • 2020 Workplan and budget were ratified in Q1, 2020 via round robin votes.

ACUTE EYE IRRITATION IN THE RABBIT/ MnSO4 (Manganese Sulphate Monohydrate)/ OECD 405 / GLP

Introduction. The study was performed to assess the irritancy potential of the test material using the model of the eye of the New Zealand white rabbit. The method was designed to meet the requirements of the following:

  • OECD Guidelines for the Testing of Chemicals No. 405, “Acute Eye Irritation/Corrosion” (adopted 24 April 2002)
  • Method B5 Acute Toxicity (Eye Irritation) of Commission Regulation (EC) No. 440/2008

Conclusion. The test material produced a maximum total score of 36 and was considered to be at least a moderate irritant (Class 5 on a 1 to 8 scale) to the rabbit eye according to a modified Kay and Calandra classification system (based on one rabbit only).

The test material was also considered to be an irritant according to EU labelling regulations Commission Directive 2001/59/EC. It is reasonable to assume that the symbol “Xi” (the indication of danger, “Irritant”) and the highest risk phase (R41, “RISK OF SERIOUS DAMAGE TO EYES”) are required here due to the evidence of irreversible ocular damage (based on one rabbit only).

To obtain the full study, please contact: reach@manganese.org.

 

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