2021 GA Meeting May 12th, 14:00-15:30



The 2020 GA meeting which normally takes place in May was postponed to November 4th due to the global pandemic. The November 4th meeting which was virtual saw 20 attendees and lasted an hour as most of the GA mandated task/decisions were addressed by way of votes prior to the meeting. Chaired by Interim Chairman Dr Bernd Friede, the meeting though brief was effective with some key decisions taken as follows:

Some highlights:

  • Executive Committee: A new Executive team was endorsed with the 2nd Vice-Chairman becoming the Chairman and Secretary General maintained to ensure continuity
  • Non-EU letter of Access Fees: Letter of Access fees and administration fees for non-EU REACH-Like regulations per substance, per legal entity for non-MARA members was established
  • Members involvement in Non-EU regulations: MARA members wishing to register substances in non-EU REACH-like regulations will only pay administration fees as they own the data generated by MARA
  • Technical update: Three dossiers updated this year lead to a new classification for manganese based UVCB’s
  • 2020 Workplan and budget were ratified in Q1, 2020 via round robin votes.


Introduction. A study was performed to assess the acute inhalation toxicity of the test item. The method used followed that described in the OECD Guidelines for Testing of Chemicals (2009) No. 403 “Acute Inhalation Toxicity” and was designed to comply with Method 82 (Inhalation) of Commission Regulation (EC) No. 440/2008, with the exception that only six animals (three males and three females) were utilized during the “limit test”.


Conclusion. No deaths occurred in a group of six rats exposed to a mean achieved atmosphere concentration of 5.17 mg/L for four hours. It was therefore considered that the acute inhalation median lethal concentration (4 hr LC50) of Mn3O4 (Erachem), in the HsdHanTM : WlST strain rat, was greater than 5.17 mg/L.


On the basis of this result, Mn304 (Erachem) does not meet the criteria for classification in the EU in accordance with both Council Directive 67/548/EEC as amended and Regulation (EC) No 1272/2008 and will not require labelling for inhalation toxicity.


To obtain the full study, please contact: reach@manganese.org


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