
A virtual (Zoom) and face-to-face meeting in Paris, France
followed by Lunch
Other Logistical information to follow nearer the time
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The 2020 GA meeting which normally takes place in May was postponed to November 4th due to the global pandemic. The November 4th meeting which was virtual saw 20 attendees and lasted an hour as most of the GA mandated task/decisions were addressed by way of votes prior to the meeting. Chaired by Interim Chairman Dr Bernd Friede, the meeting though brief was effective with some key decisions taken as follows:
Some highlights:
- Executive Committee: A new Executive team was endorsed with the 2nd Vice-Chairman becoming the Chairman and Secretary General maintained to ensure continuity
- Non-EU letter of Access Fees: Letter of Access fees and administration fees for non-EU REACH-Like regulations per substance, per legal entity for non-MARA members was established
- Members involvement in Non-EU regulations: MARA members wishing to register substances in non-EU REACH-like regulations will only pay administration fees as they own the data generated by MARA
- Technical update: Three dossiers updated this year lead to a new classification for manganese based UVCB’s
- 2020 Workplan and budget were ratified in Q1, 2020 via round robin votes.

ACUTE ORAL TOXICITY IN THE RAT – FIXED DOSE METHOD/ MnO (Manganese Oxide)/ OECD 420 / GLP
Introduction. The study was performed to assess the acute oral toxicity of the test material in the Wistar strain rat. The method was designed to meet the requirements of the following:
- OECD Guidelines for Testing of Chemicals No 420 “Acute Oral Toxicity – Fixed Dose Method” (2001)
- Method B1 bis Acute Toxicity (Oral) of Commission Regulation (EC) No. 440/2008
Conclusion. The acute oral median lethal dose (LD50) of the test material in the female Wistar strain rat was estimated to be greater than 2000 mg/kg bodyweight (Globally Harmonised Classification System - Unclassified).
To obtain the full study, please contact: reach@manganese.org