2023 Mn REACH Conference September 26-28th Thon Hotel, City Centre, Brussels

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MARA's 2023 Mn REACH Conference is scheduled to take place on September 26-28 at the Thon Hotel City Centre, Brussels.

Speakers from the Manganese Industry, other Metal Consortia, European Metal Associations and Regulatory Experts will enlighten you on the short-term risks/threats on your businesses as well as your responsibilities under the Evaluation aspect of EU REACH


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ACUTE ORAL TOXICITY IN THE RAT/ Sinter ore (Manganese ores, reduced)/ OECD 420/ GLP

Introduction. The study was performed to assess the acute oral toxicity of the test material in the Wistar strain rat. The method was designed to meet the requirements of the following:

  • OECD Guidelines for Testing of Chemicals No 420 “Acute Oral Toxicity – Fixed Dose Method” (2001)
  • Method B1 bis Acute Toxicity (Oral) of Commission Regulation (EC) No. 440/2008


Conclusion. The acute oral median lethal dose (LD50) of the test material in the female Wistar strain rat was estimated to be greater than 2000 mg/kg bodyweight (Globally Harmonised Classification System - Unclassified).


To obtain the full study, please contact: reach@manganese.org


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