General Assembly Meeting Thursday, May 5th 10:00 – 13:00

General Assembly Meeting - 2022

A virtual (Zoom) and face-to-face meeting in Paris, France

followed by Lunch

Other Logistical information to follow nearer the time




The 2020 GA meeting which normally takes place in May was postponed to November 4th due to the global pandemic. The November 4th meeting which was virtual saw 20 attendees and lasted an hour as most of the GA mandated task/decisions were addressed by way of votes prior to the meeting. Chaired by Interim Chairman Dr Bernd Friede, the meeting though brief was effective with some key decisions taken as follows:

Some highlights:

  • Executive Committee: A new Executive team was endorsed with the 2nd Vice-Chairman becoming the Chairman and Secretary General maintained to ensure continuity
  • Non-EU letter of Access Fees: Letter of Access fees and administration fees for non-EU REACH-Like regulations per substance, per legal entity for non-MARA members was established
  • Members involvement in Non-EU regulations: MARA members wishing to register substances in non-EU REACH-like regulations will only pay administration fees as they own the data generated by MARA
  • Technical update: Three dossiers updated this year lead to a new classification for manganese based UVCB’s
  • 2020 Workplan and budget were ratified in Q1, 2020 via round robin votes.

ACUTE TOXICITY TO DAPHNIA MAGNA/ FeMn slag (Ferro-manganese slag)/ OECD 202 / GLP

Introduction. A study was performed to assess the acute toxicity of the test item to Daphnia magna. The method followed that described in the OECD Guidelines for Testing of Chemicals (April 2004) No 202, "Daphnia sp, Acute lmmobilisation Test", referenced as Method 02 of Commission Regulation (EC) No. 440/2008.

Results. The 48-Hour EL*50 for the test item to Daphnia magna based on nominal loading rates was 43 mg/l loading rate WAF with 95% confidence limits of 41 - 46 mg/l loading rate WAF. The No Observed Effect Loading rate was 32 mg/l loading rate WAF.

The test item contains manganese. The test concentrations were monitored by analysis of the test samples for manganese only.

Analysis of the fresh media at 0 hours showed measured concentrations of manganese to range from 1.13 to 3.79 mg/l. Analysis of the old media at 48 hours showed measured concentrations of manganese to range from 1.16 to 3.62 mg/l.

The dissolved test item may have been one or several components of the test item. Given that toxicity cannot be attributed to a single component or mixture of components but to the test item as a whole, the results were based on nominal loading rates only.

The 48-Hour EC50 for the reference item to Daphnia magna based on nominal concentrations was 0.78 mg/l with 95% confidence limits of 0.58 - 0.72 mg/l. The No Observed Effect Concentration was 0.32 mg/l.

*EL = Effective Loading rate

To obtain the full study, please contact:




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