General Assembly Meeting Thursday, May 5th 10:00 – 13:00

General Assembly Meeting - 2022

A virtual (Zoom) and face-to-face meeting in Paris, France

followed by Lunch

Other Logistical information to follow nearer the time




The 2020 GA meeting which normally takes place in May was postponed to November 4th due to the global pandemic. The November 4th meeting which was virtual saw 20 attendees and lasted an hour as most of the GA mandated task/decisions were addressed by way of votes prior to the meeting. Chaired by Interim Chairman Dr Bernd Friede, the meeting though brief was effective with some key decisions taken as follows:

Some highlights:

  • Executive Committee: A new Executive team was endorsed with the 2nd Vice-Chairman becoming the Chairman and Secretary General maintained to ensure continuity
  • Non-EU letter of Access Fees: Letter of Access fees and administration fees for non-EU REACH-Like regulations per substance, per legal entity for non-MARA members was established
  • Members involvement in Non-EU regulations: MARA members wishing to register substances in non-EU REACH-like regulations will only pay administration fees as they own the data generated by MARA
  • Technical update: Three dossiers updated this year lead to a new classification for manganese based UVCB’s
  • 2020 Workplan and budget were ratified in Q1, 2020 via round robin votes.


Introduction. A study was performed to assess the acute toxicity of the test item to Daphnia magna. The method followed that described in the OECD Guidelines for Testing of Chemicals (April 2004) No 202, "Daphnia sp, Acute Immobilisation Test" referenced as Method C2 of Commission Regulation (EC) No. 440/2008.


Results. The 48-Hour EC50 for the test item to Daphnia magna based on nominal test concentrations was greater than 100% v/v saturated solution and correspondingly the No Observed Effect Concentration was 100% v/v saturated solution.


The test item contained a theoretical manganese content of 63% w/w. The test samples were analysed for manganese only. Analysis of the test preparations at 0 and 48 hours showed measured test concentrations to range from 6.0 to 6.1 mg/l as test item.


Given that no decline in measured concentration was observed over the test period, it was considered appropriate to calculate the results based on the mean measured test item concentrations.


The 48-Hour EC50 for the test item to Daphnia magna, based on the mean measured test concentration as test item, was greater than 6.1 mg/l and correspondingly the No Observed Effect Concentration was 6.1 mg/l.


This study showed that there were no toxic effects at saturation.


The 48-Hour EC50 for the reference item to Daphnia magna based on nominal concentrations was 0.65 mg/I with 95% confidence limits of 0.58 - 0.72 mg/l. The No Observed Effect concentration was 0.32 mg/l.


To obtain the full study, please contact:


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