ASSESSMENT OF OCULAR IRRITATION POTENTIAL/ MnO2 (Manganese dioxide)/ OECD 492 /GLP
Introduction. The purpose of this study was to determine the eye irritation potential of the test material using the SkinEthic Reconstituted Human Corneal model (HCE, SkinEthic Laboratories, Nice, France) after a treatment period of 10 minutes. The test is based on the hypothesis that irritant chemicals are able to penetrate the corneal epithelial tissue and are sufficiently cytotoxic to cause cell death.
Conclusion. According to the protocol followed the test material was considered to be a Non-Irritant (NI).
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