MARA's 2023 Mn REACH Conference is scheduled to take place on September 26-28 at the Thon Hotel City Centre, Brussels.
Speakers from the Manganese Industry, other Metal Consortia, European Metal Associations and Regulatory Experts will enlighten you on the short-term risks/threats on your businesses as well as your responsibilities under the Evaluation aspect of EU REACH
ASSESSMENT OF OCULAR IRRITATION POTENTIAL/ SiMn slag (Silicomanganese slag)/OECD 492/GLP
Introduction. The purpose of this study was to determine the eye irritation potential of the test material using the SkinEthic Reconstituted Human Corneal model (HCE, SkinEthic Laboratories, Nice, France) after a treatment period of 10 minutes. The test is based on the hypothesis that irritant chemicals are able to penetrate the corneal epithelial tissue and are sufficiently cytotoxic to cause cell death.
Conclusion. According to the protocol followed the test material was considered to be a Non-Irritant (NI).
To obtain the full study, please contact: reach@manganese.org