MARA's 2023 Mn REACH Conference is scheduled to take place on September 26-28 at the Thon Hotel City Centre, Brussels.
Speakers from the Manganese Industry, other Metal Consortia, European Metal Associations and Regulatory Experts will enlighten you on the short-term risks/threats on your businesses as well as your responsibilities under the Evaluation aspect of EU REACH
LOCAL LYMPH NODE ASSAY IN THE MOUSE/ Mn metal (Manganese metal)/ OECD 429 / GLP
Introduction. A study was performed to assess the skin sensitisation potential of the test material in the CBA/Ca strain mouse following topical application to the dorsal surface of the ear. The method was designed to meet the requirements of the following:
- OECD Guideline for the Testing of Chemicals No. 429, "Skin Sensitisation: Local Lymph Node Assay" (adopted 24 April 2002)
- Method B42 Skin Sensitisation (Local Lymph Node Assay) of Commission Regulation (EC) No. 440/2008
Conclusion. The test material was considered to be a non-sensitiser under the conditions of the test.
To obtain the full study, please contact: reach@manganese.org