LOCAL LYMPH NODE ASSAY IN THE MOUSE/ MnO (Manganese Oxide)/ OECD 429/ GLP
Introduction. A study was performed to assess the skin sensitisation potential of the test material in the CBA/Ca strain mouse following topical application to the dorsal surface of the ear. The method was designed to meet the requirements of the following:
- OECD Guideline for the Testing of Chemicals No. 429 "Skin Sensitisation: Local Lymph Node Assay" (adopted 24 April 2002)
- Method B42 Skin Sensitisation (Local Lymph Node Assay) of Commission Regulation (EC) No. 440/2008
Conclusion. The test material was considered to be a non-sensitiser under the conditions of the test.
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