2020 GA Meeting May 6th Postponed to November 4th due to COVID 19


The 2019 GA meeting which took place on Wednesday 8 May 2019 in Madrid, Spain was a resounding success. Hosted by FerroGlobe, the meeting which lasted 4 hours saw several deliberations related to the consortium governace, dossier updates and classification & labelling. Some key decisions taken by way of vote are as follows:

Some highlights:

  • Executive Committee: A new Chairmanand  a new 2nd Vice Chairman were appointed, meanwhile the 1st Vice Chiarman was maintained to enure continuity
  • Dossier updates: Reveal changes in classification and labelling if compared to the 2010 submitted dossiers
  • Approval of the 2018 workplan and budget
  • Brexit and data: Mara will continue to support REACH registration inside and outside the EU (UK REACH inclusive) but at a charge yet to be determined

TK study in Sprague-Dawley Rats/FeMn slag/EC2004/10/EC/Oral/GLP


The purpose of this study was to assess the toxicokinetics (proof of absorption) of Ferromanganese (FeMn) Slag, a by-product of the production of manganese alloys, in a seven week oral study in Sprague‑Dawley rats.  Three groups, each comprising four males and four females, received FeMn Slag at doses of 10, 100 or 1000 mg/kg/day.  A similarly constituted control group received the vehicle, corn oil, at a volume dose of 5 mL/kg/day. 

During the study, toxicokinetics (proof of absorption), clinical condition, body weight and food consumption investigations were undertaken.


There was no evidence of any significant absorption of the test material.  One intermediate dose male had quantifiable concentrations of aluminium at one and 24 hours post‑dose but, otherwise, the plasma levels of the elements measured (manganese, silicon, aluminium and barium) were all below the limit of quantification.

There were no treatment‑related clinical signs, no unscheduled deaths and no effect on bodyweight and food consumption.




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