ACUTE EYE IRRITATION IN THE RABBIT/ FeMn slag (Ferro-manganese slag)/ OECD 405/ GLP

Introduction. The study was performed to assess the irritancy potential of the test material to the eye of the New Zealand white rabbit. The method was designed to meet the requirements of the following:

• OECD Guidelines for the Testing of Chemicals No. 405 “Acute Eye Irritation/Corrosion” (adopted 24 April 2002)
• Method B5 Acute Toxicity (Eye Irritation) of Commission Regulation (EC) No. 440/2008

Conclusion. The test material produced a maximum group mean score of 10.0 and was classified as a minimal irritant (Class 3 on a 1 to 8 scale) to the rabbit eye according to a modified Kay and Calandra classification system.

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