ACUTE ORAL TOXICITY IN THE RAT – FIXED DOSE METHOD/ MnCO3 (Manganese Carbonate)/ OECD 420 / GLP

Introduction. The study was performed to assess the acute oral toxicity of the test material in the Wistar strain rat. The method was designed to meet the requirements of the following:

?          OECD Guidelines for Testing of Chemicals No 420 “Acute Oral Toxicity - Fixed Dose Method” (2001)

?          Method B1 bis Acute Toxicity (Oral) of Commission Regulation (EC) No. 440/2008

Conclusion. The acute oral median lethal dose (LD50) of the test material in the female Wistar strain rat was estimated to be greater than 2000 mg/kg bodyweight (Globally Harmonised Classification System - Unclassified).

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